Wernicke encephalopathy and extrapontine myelinolysis in pregnancy with hyperemesis gravidarum: a double jeopardy

We report a case of pregnant woman who had been suffering from hyperemesis gravidarum presented with alteration consciousness, nystagmus, generalized weakness and extrapyramidal symptoms at 16th week gestation. Magnetic resonance imaging the brain showed typical findings Wernicke's encephalopathy extrapontine myelinolysis. The clinical features responded dramatically to high dose thiamine supplementation. Wernicke should be diagnosed as early possible prevent long-term neurological sequela or death well fetal loss.